SCHEMBL8639330

SCHEMBL8639330

CC(CNC(=O)c1ccccc1O)N(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.50
KDM4E B2RXH2 6/20 0.49
HPGD P15428 6/20 0.49
LMNA P02545 6/20 0.49
HSD17B10 Q99714 5/20 0.49
ALDH1A1 P00352 5/20 0.49
POLR1A O95602 1/20 0.48
GAA P10253 2/20 0.47
MPO P05164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HIF1A Q16665 1/20 0.47
HTT P42858 4/20 0.47
NPC1 O15118 3/20 0.47
TSHR P16473 2/20 0.47
MAPT P10636 2/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NLRP1 Q9C000 1/20 0.47
CA1 P00915 1/20 0.46
CA9 Q16790 1/20 0.46
MEN1 O00255 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639360 0.85 NAAA (0.51) NAAAKDM4EHPGDLMNAHSD17B10
SCHEMBL3183106 0.83 POLB (0.59) NAAAKDM4EHPGDLMNAHSD17B10
SCHEMBL26980365 0.82 NAAA (0.54) NAAAKDM4EHPGDLMNAHSD17B10
SCHEMBL8489960 0.81 NAAA (0.53) NAAAKDM4EHPGDLMNAHSD17B10
SCHEMBL11016850 0.79 ALDH1A1 (0.58) NAAAKDM4EHPGDLMNAHSD17B10
SCHEMBL28883877 0.76 KDM4E (0.52) NAAAKDM4EHPGDLMNAHSD17B10
Salcaprozic Acid SCHEMBL29036110 0.75 NAAA (0.60) NAAAKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL1797745 0.74 CA1 (0.68) NAAAKDM4EHPGDLMNAHSD17B10
SCHEMBL8639778 0.74 NAAA (0.60) NAAAKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL13038296 0.74 NAAA (0.53) NAAAKDM4EHPGDLMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5753407-A Polyamic acid composition KABUSHIKI KAISHA TOSHIBA (JP) 1998-05-19 US disclosed
US-5585217-A Polyamic acid composition KABUSHIKI KAISHA TOSHIBA (JP) 1996-12-17 US disclosed