Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304924 | 0.89 | POLB (0.44) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL7532354 | 0.89 | POLB (0.42) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL9230285 | 0.88 | POLB (0.47) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL9230291 | 0.85 | ABL1 (0.41) | POLBABL1RIN1P2RX3PARP1 | |
| SCHEMBL2707232 | 0.76 | SRC (0.39) | POLBP2RX3PARP1MEN1KMT2A | |
| SCHEMBL9230297 | 0.74 | ABL1 (0.40) | POLBABL1RIN1PARP1SRC | |
| SCHEMBL2707643 | 0.73 | MMP2 (0.59) | KDM4EPKMMEN1KMT2AHTRA1 | |
| SCHEMBL2709145 | 0.73 | MMP2 (0.59) | KDM4EPKMMEN1KMT2AHTRA1 | |
| SCHEMBL9230690 | 0.72 | ABCB1 (0.40) | POLBABL1RIN1PARP1SRC | |
| SCHEMBL8639604 | 0.72 | USP30 (0.44) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646596-A1 | Nucleic acid binding oligomers having C-branches for therapy and diagnosis | BAYER AG (DE) | 1995-04-05 | — | — | EP | disclosed |