Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387084 | 0.91 | LMNA (1.00) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL14438979 | 0.89 | PDE4A (0.78) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL6168317 | 0.86 | LMNA (0.90) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL410475 | 0.83 | PDE4A (0.70) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL3831106 | 0.79 | PDE4A (1.00) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL27019339 | 0.78 | PDE4A (0.64) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL2242634 | 0.78 | PDE4A (0.62) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL10619199 | 0.78 | SMN1; SMN2 (0.74) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| Terbuthylazine SCHEMBL9715292 | 0.78 | KMT2A (0.74) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA | |
| Terbuthylazine SCHEMBL29623015 | 0.78 | KMT2A (0.74) | PDE4ACYP1A2CYP2C19SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785717-B1 | STABLE MIXTURE CONTAINING WATER AND METAZACHLOR | BASF AG (DE) | 1998-08-19 | — | — | EP | disclosed |
| EP-0088049-B1 | HERBICIDAL MIXTURES | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0088049-A1 | Herbicidal mixtures | CIBA-GEIGY AG (CH) | 1983-09-07 | — | — | EP | disclosed |
| US-4309210-A | HERBICIDE AND SAFENING AGENT | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| EP-0012717-A1 | Method and composition for the selective pre-emergent control of weeds in cereal cultures | CIBA-GEIGY AG (CH) | 1980-06-25 | — | — | EP | disclosed |
| US-4066437-A | TRIAZOLIDINE COMPOUNDS USEFUL AS HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |