Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641186 | 0.80 | KDM1A (0.36) | KIF11CXCR3CHKAPTGS1KDM1A | |
| SCHEMBL8640336 | 0.79 | NISCH (0.33) | NISCH | |
| SCHEMBL8638457 | 0.78 | MEN1 (0.34) | KIF11PTGS2 | |
| SCHEMBL8638455 | 0.78 | MEN1 (0.34) | KIF11PTGS2 | |
| SCHEMBL22475240 | 0.77 | CYP3A4 (0.36) | — | |
| SCHEMBL8641402 | 0.77 | HTR2C (0.34) | — | |
| SCHEMBL13003248 | 0.77 | ROCK1 (0.37) | KIF11 | |
| SCHEMBL8639440 | 0.77 | KDM1A (0.35) | KIF11CXCR3CHKAKDM1ARCOR1 | |
| SCHEMBL23280225 | 0.77 | NISCH (0.32) | NISCH | |
| SCHEMBL8637216 | 0.75 | TLR8 (0.34) | KIF11CXCR3CHKAKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |