Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752163 | 0.89 | GPR88 (0.37) | NPC1RAB9ASMN1; SMN2CTSBF10 | |
| SCHEMBL7600401 | 0.89 | HSD17B10 (0.51) | HSD17B10 | |
| Hydrochloric Acid SCHEMBL6926940 | 0.89 | GPR88 (0.37) | NPC1RAB9ASMN1; SMN2CTSBF10 | |
| SCHEMBL8641877 | 0.84 | GPR88 (0.36) | HSD17B10 | |
| SCHEMBL8641846 | 0.84 | MMP3 (0.36) | F10PRSS1HSD17B10F2 | |
| SCHEMBL8641490 | 0.82 | HSD17B10 (0.45) | NPC1RAB9ASMN1; SMN2CTSBCTSL | |
| SCHEMBL8639837 | 0.81 | GPR88 (0.37) | CTSBF10PRSS1F2HTT | |
| SCHEMBL7621710 | 0.81 | GPR88 (0.39) | NPC1RAB9ASMN1; SMN2CTSB | |
| Hydrochloric Acid SCHEMBL6928254 | 0.81 | GPR88 (0.38) | NPC1RAB9ASMN1; SMN2CTSB | |
| SCHEMBL7598817 | 0.79 | HSD17B10 (0.44) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766687-B1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 1998-08-05 | — | — | EP | disclosed |
| US-5739123-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR TREATING CARDIOVASCULAR DISEASES | ZAMBON GROUP S.P.A. (IT) | 1998-04-14 | — | — | US | disclosed |
| EP-0766687-A1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035302-A1 | PHOSPHINIC ACID DERIVATIVES WITH METALLOPEPTIDASE INHIBITORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1995-12-28 | — | — | WO | disclosed |