SCHEMBL8639841

SCHEMBL8639841

CCCCCCCCC1C=CC(c2ccc(C)cc2)=CC1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.36
HTT P42858 1/20 0.33
GCGR P47871 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MGAT2 Q10469 1/20 0.30
TLR8 Q9NR97 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8643070 1.00 GRM2 (0.36) GRM2HTTGCGRL3MBTL1MGAT2
SCHEMBL8638473 1.00 GRM2 (0.36) GRM2HTTGCGRL3MBTL1MGAT2
SCHEMBL8638340 0.88 ROCK1 (0.30)
SCHEMBL8639049 0.87 LMNA (0.33) L3MBTL1
SCHEMBL8640877 0.87 GRM2 (0.37) GRM2GCGRTLR8
SCHEMBL8640995 0.87 GRM2 (0.37) GRM2GCGRTLR8
SCHEMBL8636705 0.87 GRM2 (0.37) GRM2GCGRTLR8
SCHEMBL8637039 0.87 GRM2 (0.37) GRM2GCGRTLR8
SCHEMBL8637984 0.87 GRM2 (0.37) GRM2GCGRTLR8
SCHEMBL8643053 0.87 LMNA (0.33) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0571652-B1 Liquid crystalline substituted dihydrobenzene derivatives CITIZEN WATCH CO LTD (JP) 1998-08-05 EP disclosed
US-5342546-A Liquid crystal compositions L.C.C. CONSULTANTS CO., LTD. (JP) 1994-08-30 US disclosed
EP-0571652-A1 Liquid crystalline substituted dihydrobenzene derivatives L.C.C. CONSULTANTS CO., LTD. (JP) 1993-12-01 EP disclosed