SCHEMBL8640209

SCHEMBL8640209

O=C(Oc1cc2ccc(O)cc2oc1=O)ON1C(=O)CCC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
MIF P14174 9/20 0.45
MEN1 O00255 7/20 0.45
KMT2A Q03164 7/20 0.45
KDM4E B2RXH2 3/20 0.45
GLA P06280 3/20 0.45
MAPT P10636 3/20 0.45
S1PR4 O95977 2/20 0.45
GAA P10253 2/20 0.45
S1PR1 P21453 2/20 0.45
HSD17B3 P37058 1/20 0.45
ESR2 Q92731 1/20 0.43
PFKFB3 Q16875 1/20 0.43
HTT P42858 1/20 0.42
PTGS1 P23219 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
NPC1 O15118 3/20 0.41
RXFP1 Q9HBX9 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634844 0.82 MEN1 (0.54) MEN1KMT2AKDM4EGLAMAPT
SCHEMBL591197 0.80 MIF (0.60) MIFMEN1KMT2AKDM4EGLA
SCHEMBL30267413 0.80 MIF (0.60) MIFMEN1KMT2AKDM4EGLA
SCHEMBL11973913 0.78 POLB (0.47) POLBMIFMEN1KMT2AKDM4E
SCHEMBL8764982 0.77 POLB (0.57) POLBMIFMEN1KMT2AKDM4E
SCHEMBL2162276 0.77 CA9 (0.65) POLBMIFMEN1KMT2AKDM4E
SCHEMBL10067520 0.77 MIF (0.44) MIFMEN1KMT2AKDM4EGLA
SCHEMBL27527189 0.74 POLB (0.53) POLBMIFMEN1KMT2AKDM4E
SCHEMBL18141852 0.71 POLB (0.59) POLBMIFMEN1KMT2AKDM4E
SCHEMBL250387 0.71 MIF (0.68) POLBMIFMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558740-B1 PROBE COMPOSITION FOR GENOME IDENTIFICATION AND METHODS VYSIS INC (US) 1998-08-05 EP claimed