Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590757 | 0.83 | KCNA3 (0.50) | KCNA3SIGMAR1CTSKCNR1CNR2 | |
| SCHEMBL3150583 | 0.74 | KDM4E (0.47) | KDM4E | |
| SCHEMBL8656217 | 0.72 | SIGMAR1 (0.42) | HTR2AHTR2CSIGMAR1 | |
| SCHEMBL6015848 | 0.71 | SIGMAR1 (0.44) | HTR2AHTR2CSIGMAR1 | |
| SCHEMBL8319222 | 0.71 | SIGMAR1 (0.44) | HTR2AHTR2CSIGMAR1 | |
| SCHEMBL8653533 | 0.70 | ALDH1A1 (0.48) | KDM4E | |
| SCHEMBL8653071 | 0.70 | ACACB (0.50) | KDM4E | |
| SCHEMBL8452782 | 0.68 | HTR2A (0.44) | HTR2AHTR2CSIGMAR1 | |
| SCHEMBL8454162 | 0.68 | HTR2A (0.44) | HTR2AHTR2CSIGMAR1 | |
| SCHEMBL30684404 | 0.68 | HTR2A (0.44) | HTR2AHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5721230-A | ANTIINFLAMMATORY AGENT, VIRICIDES; TREATING CARDIOVASCULAR DISORDER, RESPIRATORY SYSTEM DISORDER, THROMBOSIS, DIABETES, ALOPECIA | HOFFMANN-LA ROCHE INC. (US) | 1998-02-24 | — | — | US | disclosed |