Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640174 | 0.99 | LMNA (0.33) | MAPTTP53NPC1NFKB1MAPK1 | |
| SCHEMBL8639049 | 0.99 | LMNA (0.33) | MAPTTP53NPC1NFKB1MAPK1 | |
| SCHEMBL8637774 | 0.99 | LMNA (0.33) | MAPTTP53NPC1NFKB1MAPK1 | |
| SCHEMBL8636298 | 0.99 | LMNA (0.33) | MAPTTP53NPC1NFKB1MAPK1 | |
| SCHEMBL8643053 | 0.99 | LMNA (0.33) | MAPTTP53NPC1NFKB1MAPK1 | |
| SCHEMBL8638434 | 0.96 | NPC1 (0.33) | MAPTTP53NPC1NFKB1MAPK1 | |
| SCHEMBL8639829 | 0.90 | KDM1A (0.30) | — | |
| SCHEMBL8639841 | 0.86 | GRM2 (0.36) | L3MBTL1 | |
| SCHEMBL8643070 | 0.86 | GRM2 (0.36) | L3MBTL1 | |
| SCHEMBL8636477 | 0.86 | GRM2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |