SCHEMBL8640417

SCHEMBL8640417

O=C(Oc1ccc(Cl)c(Cl)c1Cl)c1ccc(O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 1/20 0.44
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44
CA14 Q9ULX7 3/20 0.44
FABP3 P05413 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.41
ESR1 P03372 4/20 0.41
ESR2 Q92731 3/20 0.41
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CHRM1 P11229 1/20 0.39
TSHR P16473 1/20 0.39
SLC6A2 P23975 1/20 0.39
KDR P35968 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10786579 0.83 SMN1; SMN2 (0.44) KMT2AMEN1FABP3MRGPRX4MAPK1
SCHEMBL768050 0.81 ESR1 (0.49) SENP1KMT2AMEN1CA12CA1
SCHEMBL1975083 0.77 HPGD (0.51) SENP1KMT2AMEN1CA12CA1
SCHEMBL767466 0.77 SENP1 (0.50) SENP1KMT2AMEN1CA12CA1
SCHEMBL777889 0.77 KMT2A (0.46) SENP1KMT2AMEN1ESR1ESR2
SCHEMBL10604766 0.77 KMT2A (0.47) KMT2AMEN1MRGPRX4ESR1ESR2
SCHEMBL121772 0.75 FABP3 (0.49) FABP3MRGPRX4MAPK1TSHRTDP1
SCHEMBL2929232 0.75 FABP3 (0.49) FABP3MRGPRX4MAPK1TSHRTDP1
SCHEMBL30552290 0.75 FABP3 (0.49) FABP3MRGPRX4MAPK1TSHRTDP1
SCHEMBL10854654 0.75 MAPT (0.50) KMT2AMEN1FABP3MRGPRX4ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626272-B1 Heat-sensitive recording material OJI PAPER CO (JP) 1998-08-12 EP disclosed
US-5447899-A Paper laminate for thermosensitivity NEW OJI PAPER CO., LTD. (JP) 1995-09-05 US disclosed
EP-0626272-A1 Heat-sensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-11-30 EP disclosed