Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 7/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613851 | 0.88 | PTGER1 (0.44) | MAOBCCR5SLC6A4LMNAPTGER1 | |
| SCHEMBL8613429 | 0.87 | USP28 (0.44) | CCR5SLC6A4LMNAPTGER1ALDH1A1 | |
| SCHEMBL8616112 | 0.86 | USP28 (0.45) | MAOBCCR5SLC6A4LMNAPTGER1 | |
| SCHEMBL8616654 | 0.85 | USP28 (0.43) | CCR5SLC6A4LMNAPTGER1ALDH1A1 | |
| SCHEMBL8614619 | 0.84 | KDM1A (0.47) | MAOBCCR5SLC6A4LMNAPTGER1 | |
| SCHEMBL8616572 | 0.84 | KDM1A (0.47) | MAOBCCR5SLC6A4LMNAPTGER1 | |
| SCHEMBL8612028 | 0.84 | FEN1 (0.40) | PTGER1RAB9ASMN1; SMN2 | |
| SCHEMBL8643887 | 0.83 | ERN1 (0.48) | MAOBCCR5SLC6A4PTGER1ALDH1A1 | |
| SCHEMBL8617922 | 0.82 | KDM1A (0.40) | PTGER1RAB9ASMN1; SMN2 | |
| SCHEMBL8613734 | 0.81 | FEN1 (0.41) | PTGER1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0665836-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |