Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 1/20 | 0.44 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616654 | 0.99 | USP28 (0.43) | USP28USP25HTTCCR5SLC6A4 | |
| SCHEMBL8616112 | 0.91 | USP28 (0.45) | USP28USP25HTTCCR5SLC6A4 | |
| SCHEMBL8613441 | 0.90 | KDM1A (0.40) | USP28USP25HTTPTGER1RAB9A | |
| SCHEMBL8613851 | 0.90 | PTGER1 (0.44) | USP28USP25HTTCCR5SLC6A4 | |
| SCHEMBL8640424 | 0.87 | MAOB (0.43) | USP28USP25HTTCCR5SLC6A4 | |
| SCHEMBL8613340 | 0.87 | ERN1 (0.41) | USP28USP25PTGER1RAB9AGSTP1 | |
| SCHEMBL8616558 | 0.87 | GSTP1 (0.56) | LMNARAB9AGSTP1RXRARXRB | |
| SCHEMBL8617922 | 0.86 | KDM1A (0.40) | PTGER1RAB9AGSTP1KDM1ARXRA | |
| SCHEMBL8612028 | 0.85 | FEN1 (0.40) | PTGER1RAB9AGSTP1KDM1ARXRA | |
| SCHEMBL8613871 | 0.85 | CYP11B1 (0.41) | PTGER1RAB9ALRRK2KDM1ARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |