Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682348 | 0.83 | HPGD (0.68) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL18542949 | 0.83 | ALDH1A1 (0.70) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL9263148 | 0.82 | HPGD (0.66) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL11704529 | 0.81 | HPGD (0.74) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL28879832 | 0.81 | ALDH1A1 (0.80) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL9282371 | 0.80 | HPGD (0.62) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL8319802 | 0.79 | HPGD (0.72) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL10546402 | 0.78 | HPGD (0.70) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL11627330 | 0.78 | HPGD (0.70) | HPGDALDH1A1POLBRAB9AKDM4E | |
| SCHEMBL11077045 | 0.78 | HPGD (0.70) | HPGDALDH1A1POLBRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756822-A | ANTIULCER | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5672597-A | ANTIULCER AGENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0673925-A1 | ACETAMIDE DERIVATIVE | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1995-09-27 | — | — | EP | disclosed |