Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 6/20 | 0.63 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639790 | 0.94 | MTNR1A (0.57) | NQO2MTNR1AMTNR1B | |
| SCHEMBL8644423 | 0.93 | MTNR1A (0.57) | NQO2MTNR1AMTNR1B | |
| SCHEMBL8646700 | 0.90 | MTNR1A (0.61) | NQO2MTNR1AMTNR1B | |
| SCHEMBL8639949 | 0.87 | MTNR1A (0.49) | NQO2MTNR1AMTNR1B | |
| SCHEMBL8646238 | 0.86 | MTNR1A (0.48) | NQO2MTNR1AMTNR1B | |
| SCHEMBL9017426 | 0.84 | MTNR1A (0.56) | NQO2MTNR1AMTNR1B | |
| SCHEMBL9017425 | 0.84 | MTNR1A (0.57) | NQO2MTNR1AMTNR1B | |
| SCHEMBL8643630 | 0.84 | MTNR1A (0.60) | NQO2MTNR1AMTNR1B | |
| SCHEMBL8641029 | 0.82 | MTNR1A (0.56) | NQO2MTNR1AMTNR1B | |
| SCHEMBL9017429 | 0.81 | MTNR1A (0.49) | NQO2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736578-A | TREATMENT OF SLEEP DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-07 | — | — | US | claimed |
| CN-1145895-A | New amido-ethyl substituted fluorene compound and its prepn. | BRISTOL MYERS SQUIBB CO (US) | 1997-03-26 | — | — | CN | claimed |
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| US-5736578-A | TREATMENT OF SLEEP DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| CN-1145895-A | New amido-ethyl substituted fluorene compound and its prepn. | BRISTOL MYERS SQUIBB CO (US) | 1997-03-26 | — | — | CN | disclosed |
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |