Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.48 |
| ▸ | NQO2 | P16083 | 13/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639949 | 0.88 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2LMNA | |
| SCHEMBL8646700 | 0.88 | MTNR1A (0.61) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8640441 | 0.86 | NQO2 (0.63) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8643630 | 0.85 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL9017425 | 0.83 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9017426 | 0.83 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9017429 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1BNQO2LMNA | |
| SCHEMBL8641737 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8639790 | 0.81 | MTNR1A (0.57) | MTNR1AMTNR1BNQO2NPSR1 | |
| SCHEMBL8638751 | 0.81 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | claimed |
| US-5736578-A | TREATMENT OF SLEEP DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-07 | — | — | US | disclosed |
| EP-0747345-A2 | Ethylamido fluorenes and improved method of making same | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |