Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | GLB1 | P16278 | 3/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065657 | 0.74 | BCHE (0.46) | KMT2AMEN1BCHEACHESCN2A | |
| SCHEMBL1752692 | 0.74 | KMT2A (0.38) | KMT2AMEN1BCHEACHEMAPT | |
| SCHEMBL4925470 | 0.72 | BCHE (0.60) | KMT2AMEN1BCHEACHEMAPT | |
| SCHEMBL4642628 | 0.71 | BCHE (0.50) | KMT2AMEN1BCHEACHESCN2A | |
| SCHEMBL6413848 | 0.68 | HTR2A (0.51) | KMT2AMEN1BCHEACHEMAPT | |
| SCHEMBL9287125 | 0.66 | BCHE (0.51) | KMT2AMEN1BCHEACHESCN2A | |
| SCHEMBL3259666 | 0.66 | BCHE (0.89) | KMT2AMEN1BCHEACHESIGMAR1 | |
| SCHEMBL4721968 | 0.64 | BCHE (0.49) | KMT2AMEN1BCHEACHEMAPT | |
| SCHEMBL4722883 | 0.62 | BCHE (0.46) | KMT2AMEN1BCHEACHEMAPT | |
| SCHEMBL29004430 | 0.62 | SIGMAR1 (0.40) | KMT2AMEN1BCHEACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837702-A | HAVING POTASSIUM CHANNEL ACTIVATING ACTIVITY USEFUL AS CARDIOVASCULAR AGENTS AND TREATMENT OF ISCHEMIA | BRISTOL-MYERS SQUIBB CO. (US) | 1998-11-17 | — | — | US | disclosed |
| US-5629429-A | Process for preparing 4-arylamino-benzopyran and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| CN-1107473-A | 4-Arylamino-benzopyran and related compounds | BRISTOL MYERS SQUIBB CO (US) | 1995-08-30 | — | — | CN | disclosed |
| CN-1107473-A | 4-Arylamino-benzopyran and related compounds | BRISTOL MYERS SQUIBB CO (US) | 1995-08-30 | — | — | CN | disclosed |
| EP-0648758-A1 | 4-Arylamino-benzopyran and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |