Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29004430 | 0.88 | SIGMAR1 (0.40) | BCHEACHEKDM4EHTR2ALMNA | |
| SCHEMBL4642628 | 0.80 | BCHE (0.50) | BCHEACHESCN2AKDM4EMEN1 | |
| SCHEMBL27871198 | 0.75 | SIGMAR1 (0.47) | HTR2ALMNACHRM2CYP3A4CYP2D6 | |
| SCHEMBL8640487 | 0.74 | KMT2A (0.44) | BCHEACHESCN2AKDM4ETP53 | |
| SCHEMBL27842888 | 0.73 | MAOB (0.44) | BCHEACHEKDM4EHTR2ALMNA | |
| SCHEMBL27759010 | 0.73 | MAOB (0.44) | BCHEACHEKDM4EHTR2ALMNA | |
| SCHEMBL3079121 | 0.73 | MAOB (0.44) | BCHEACHEKDM4EHTR2ALMNA | |
| SCHEMBL28661848 | 0.71 | SIGMAR1 (0.41) | KDM4EHTR2ALMNATP53CHRM2 | |
| SCHEMBL29546963 | 0.71 | HTR6 (0.46) | BCHEACHEKDM4EHTR2ALMNA | |
| SCHEMBL2641527 | 0.71 | HTR6 (0.46) | BCHEACHEKDM4EHTR2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737547-B1 | Compositions containing and methods of using N-acyl-1H-aminoindenes | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2004-05-18 | — | — | US | disclosed |
| WO-2000038673-A1 | COMPOSITIONS CONTAINING AND METHODS OF USING N-ACYL-1H-AMINOINDENES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2000-07-06 | — | — | WO | disclosed |
| CN-1216986-A | Isoxazole derivatives | SANKYO CO (JP) | 1999-05-19 | — | — | CN | disclosed |