Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475313 | 0.84 | CHRM2 (0.51) | CHRM2TSHRCYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL29087393 | 0.84 | ALDH1A1 (0.55) | CHRM2TSHRCYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL29087377 | 0.83 | TSHR (0.49) | CHRM2TSHRCYP2D6ALDH1A1CHRM3 | |
| SCHEMBL476242 | 0.81 | OPRL1 (0.60) | CHRM2TSHRCYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL3406327 | 0.81 | CYP3A4 (0.58) | CHRM2TSHRCYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL29388865 | 0.80 | HSD11B1 (0.50) | CHRM2ALDH1A1CHRM3OPRL1LMNA | |
| SCHEMBL3671285 | 0.80 | HSD11B1 (0.50) | CHRM2ALDH1A1CHRM3OPRL1LMNA | |
| Hydrochloric Acid SCHEMBL2158958 | 0.80 | POLB (0.61) | CHRM2TSHRCYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL3905400 | 0.80 | OPRL1 (0.63) | CHRM2TSHRCYP2D6ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL21047312 | 0.79 | HSD11B1 (0.49) | CHRM2ALDH1A1CHRM3OPRL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824690-A | TREATING ASTHMA, COUGH | HOECHST MARION ROUSSEL INC. (US) | 1998-10-20 | — | — | US | disclosed |