Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.54 |
| ▸ | TSHR | P16473 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 8/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30631745 | 0.71 | HSD17B10 (0.77) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL29364629 | 0.71 | HSD17B10 (1.00) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL54380 | 0.71 | HSD17B10 (1.00) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL11832897 | 0.71 | HSD17B10 (0.77) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL9621812 | 0.70 | HSD17B10 (0.50) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL68191 | 0.70 | HSD17B10 (0.77) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL827930 | 0.70 | HSD17B10 (1.00) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL5843023 | 0.70 | HPGD (0.36) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL4542827 | 0.69 | HSD17B10 (0.65) | HSD17B10TSHRHPGDMAPK1CASP1 | |
| SCHEMBL28190361 | 0.68 | HSD17B10 (0.93) | HSD17B10TSHRHPGDMAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664014-B1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL NV (NL) | 1998-08-19 | — | — | EP | disclosed |
| EP-0824096-A2 | Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters | Akzo Nobel N.V. (NL) | 1998-02-18 | — | — | EP | disclosed |