Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387726 | 0.78 | ALDH1A1 (0.45) | HSD17B10TSHRCYP3A4ALDH1A1HPGD | |
| SCHEMBL69521 | 0.73 | HSD17B10 (0.50) | HSD17B10TSHRCYP3A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL29904874 | 0.70 | HSD17B10 (0.40) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL8640503 | 0.70 | HSD17B10 (0.54) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL5372785 | 0.70 | HSD17B10 (0.40) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL11368863 | 0.69 | TSHR (0.50) | HSD17B10TSHRCYP3A4RECQLALDH1A1 | |
| SCHEMBL5363872 | 0.69 | BACE1 (0.50) | HSD17B10CYP3A4ALDH1A1HPGDLMNA | |
| Bithionoloxide SCHEMBL69373 | 0.69 | HSD17B10 (0.56) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL727419 | 0.68 | CA1 (0.50) | CYP3A4TTRALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8872103 | 0.67 | HSD17B10 (1.00) | HSD17B10TSHRCYP3A4TTRRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128429-A | Low temperature block polymerization without randomization | RAYCHEM LIMITED (GB) | 1992-07-07 | — | — | US | disclosed |
| EP-0154506-B1 | PREPARATION OF ORGANIC POLYMERS | RAYCHEM LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-4999411-A | Polythioethers, polythiocarbonates, polythioamides, polythioimides | RAYCHEM LIMITED (GB) | 1991-03-12 | — | — | US | disclosed |
| US-4960835-A | ENGINEERING THERMOPLASTICS | RAYCHEM LIMITED (GB) | 1990-10-02 | — | — | US | disclosed |
| US-4845179-A | CONDENSATION POLYMERIZATION | RAYCHEM LIMITED (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0154506-A2 | Preparation of organic polymers | RAYCHEM LIMITED (GB) | 1985-09-11 | — | — | EP | disclosed |