SCHEMBL8640591

SCHEMBL8640591

C=C(CC(=O)O)C(=O)OC(C)(C)CC(C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.33
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
FPR2 P25090 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8640588 0.86 MMP8 (0.33) MMP8TSHR
SCHEMBL28725093 0.78 MMP8 (0.36) MMP8GAASMN1; SMN2
SCHEMBL23494347 0.78 TSHR (0.48) MMP8TSHR
SCHEMBL7085941 0.77 ALOX15 (0.39) ALOX15HSD17B10TSHRGAA
SCHEMBL10396149 0.76 ALOX15 (0.38) ALOX15HSD17B10
SCHEMBL8639457 0.75 ALOX15 (0.34) ALOX15HSD17B10
SCHEMBL4925405 0.74 ALOX15 (0.36) ALOX15HSD17B10
Propane SCHEMBL8640596 0.74 ALOX15 (0.36) ALOX15HSD17B10GAA
SCHEMBL29310462 0.74 EGLN1 (0.35) MMP8
SCHEMBL8643454 0.73 ALOX15 (0.31) ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5851422-A Polymeric material for liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1998-12-22 US disclosed
EP-0790289-A1 Polymeric material for liquid crystal/polymer composite film, liquid crystal/polymer composite film, record display medium, and use thereof DAI NIPPON PRINTING CO., LTD. (JP) 1997-08-20 EP disclosed