Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640104 | 0.98 | LMNA (0.33) | OR51E2LMNA | |
| Hydrochloric Acid SCHEMBL30832409 | 0.98 | LMNA (0.33) | OR51E2LMNA | |
| SCHEMBL26378538 | 0.91 | CRBN (0.31) | CRBN | |
| SCHEMBL33525605 | 0.88 | ALDH1A1 (0.32) | LMNACRBN | |
| SCHEMBL12405032 | 0.86 | TRIM24 (0.32) | OR51E2 | |
| SCHEMBL12028806 | 0.86 | — | — | |
| SCHEMBL7613904 | 0.86 | LMNA (0.38) | LMNACRBN | |
| Hydrochloric Acid SCHEMBL10802250 | 0.84 | LMNA (0.40) | LMNA | |
| SCHEMBL12405026 | 0.78 | GAA (0.35) | — | |
| SCHEMBL18766459 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667860-B1 | AZA SPIRO ALKANES DERIVATIVES AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1998-08-19 | — | — | EP | disclosed |
| US-5610161-A | 1-AZASPIROALKANE DERIVATIVES; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS; EATING DISORDERS | THE BOOTS COMPANY PLC (GB) | 1997-03-11 | — | — | US | disclosed |
| EP-0667860-A1 | AZA SPIRO ALKANES DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994011346-A1 | AZA SPIRO ALKANES DERIVATIVES AS THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1994-05-26 | — | — | WO | disclosed |