Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595609 | 0.86 | HSD17B10 (0.55) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL29663733 | 0.86 | HSD17B10 (0.55) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL29720512 | 0.83 | TSHR (0.60) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL305189 | 0.83 | TSHR (0.60) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL2215984 | 0.81 | TSHR (0.57) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL8820666 | 0.81 | TSHR (0.57) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| Triclofenol SCHEMBL11818770 | 0.80 | HSD17B10 (0.64) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL69259 | 0.78 | HSD17B10 (0.80) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 | |
| SCHEMBL69493 | 0.78 | ALOX15 (0.50) | TSHRHPGDCYP3A4TDP1ALOX15 | |
| SCHEMBL30733854 | 0.78 | HSD17B10 (0.60) | TSHRHSD17B10HPGDCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664014-B1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL NV (NL) | 1998-08-19 | — | — | EP | disclosed |
| EP-0824096-A2 | Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters | Akzo Nobel N.V. (NL) | 1998-02-18 | — | — | EP | disclosed |
| EP-0664014-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | Akzo Nobel N.V. (NL) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008269-A1 | NLO SIDE CHAIN POLYMERS HAVING LOW OPTICAL LOSS | AKZO NOBEL N.V. (NL) | 1994-04-14 | — | — | WO | disclosed |