Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 8/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | TACR2 | P21452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8639237 | 0.84 | ADORA1 (0.49) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL5091129 | 0.81 | ADORA1 (1.00) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL3217333 | 0.78 | ADORA1 (0.70) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL3210466 | 0.78 | ADORA1 (0.70) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL7387472 | 0.76 | ADORA1 (0.62) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| Hydrochloric Acid SCHEMBL9597611 | 0.75 | ADORA1 (0.60) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL7016763 | 0.74 | ADORA1 (0.64) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL9597257 | 0.73 | ADORA1 (0.57) | ADORA1ADORA3ADORA2AGAAKMT2A | |
| SCHEMBL7018191 | 0.73 | ADORA1 (0.57) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL31569110 | 0.71 | ADORA1 (0.47) | ADORA1ADORA3ADORA2ANOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849753-A | Pyridyl imidazole derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-12-15 | — | — | US | disclosed |
| EP-0743943-A1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021838-A1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-08-17 | — | — | WO | disclosed |