Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640873 | 0.84 | ADORA1 (0.68) | ADORA1ADORA3ADORA2ANOS1NOS2 | |
| SCHEMBL8638332 | 0.83 | ADORA1 (0.71) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5098257 | 0.73 | ADORA1 (0.75) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8641790 | 0.73 | PARP1 (0.39) | PI4KAPI4K2BPI4K2API4KBNOS1 | |
| SCHEMBL9041424 | 0.73 | NOS1 (0.56) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7386115 | 0.71 | ADORA1 (0.53) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7383805 | 0.71 | ADORA1 (0.53) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7383935 | 0.70 | ADORA1 (0.48) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7852563 | 0.69 | ADORA3 (0.48) | ADORA1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7851022 | 0.69 | GCGR (0.48) | ADORA1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849753-A | Pyridyl imidazole derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-12-15 | — | — | US | disclosed |
| EP-0743943-A1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021838-A1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-08-17 | — | — | WO | disclosed |