Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641765 | 0.79 | MGLL (0.34) | — | |
| SCHEMBL8642246 | 0.79 | MGLL (0.30) | — | |
| SCHEMBL16728339 | 0.79 | — | — | |
| SCHEMBL3906731 | 0.76 | — | — | |
| SCHEMBL3906729 | 0.76 | — | — | |
| SCHEMBL7938647 | 0.74 | MEN1 (0.41) | GAAALDH1A1 | |
| SCHEMBL4182737 | 0.74 | KMT2A (0.31) | — | |
| SCHEMBL24140268 | 0.72 | KMT2A (0.35) | — | |
| SCHEMBL7942334 | 0.71 | RAB9A (0.35) | ALDH1A1RAB9ACHRM2CHRM1CHRM3 | |
| SCHEMBL22779194 | 0.70 | TDP1 (0.39) | CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750735-A | CHEMICAL INTERMEDIATES FOR ANTIBIOTICS | AMERICAN CYANAMID COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5744465-A | Method of inhibiting a β-lactamase enzyme by administering novel 2-thiosubstituted carbapenems | AMERICAN CYANAMID COMPANY (US) | 1998-04-28 | — | — | US | disclosed |