SCHEMBL8640915

SCHEMBL8640915

CCCCOCN(COCCCC)c1nc(-c2ccccc2)nc(N(COCCCC)COCCCC)n1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
GBA1 P04062 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
ACP1 P24666 2/20 0.39
MAPT P10636 3/20 0.39
MAPK1 P28482 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NR1H3 Q13133 1/20 0.38
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.37
HPGD P15428 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ADORA3 P0DMS8 1/20 0.36
ADORA1 P30542 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21414071 0.95 BCHE (0.38) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL16361833 0.95 NUDT1 (0.38) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL13140684 0.93 BCHE (0.37) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL438953 0.93 BCHE (0.37) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL15943014 0.93 BCHE (0.37) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL14123304 0.93 L3MBTL1 (0.47) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL16408494 0.92 BCHE (0.38) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL11029614 0.91 BCHE (0.37) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL439807 0.89 BCHE (0.35) BCHEACHEGBA1L3MBTL1ACP1
SCHEMBL13140700 0.86 POLB (0.39) GBA1L3MBTL1ACP1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8029957-B2 Photoreceptor with overcoat layer XEROX CORPORATION (US) 2011-10-04 US disclosed
US-20070281228-A1 PHOTORECEPTOR WITH OVERCOAT LAYER XEROX CORPORATION (US) 2007-12-06 US disclosed
EP-0497342-B1 Negative photoresist composition SUMITOMO CHEMICAL CO (JP) 1998-08-05 EP disclosed
US-5304456-A Negative photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-19 US disclosed
EP-0497342-A2 Negative photoresist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-08-05 EP disclosed