Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 2/20 | 0.57 |
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | MITF | O75030 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | GFER | P55789 | 1/20 | 0.77 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.77 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | FURIN | P09958 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8643727 | 0.93 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL63594 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1271678 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6289307 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL1270594 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL562469 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4092959 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6290330 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL22289568 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6290623 | 0.88 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821320-A | MIXING AROMATIC DIAMINE DIHYDROCHLORIDE OR SULFATE WITH AROMATIC ACID DIANHYDRIDE, HEATING TO DEHYDRATE AND CONDENSE | PETROLEUM ENERGY CENTER (JP) | 1998-10-13 | — | — | US | disclosed |