Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15184778 | 1.00 | HTR7 (0.39) | HTR7ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL15184770 | 0.95 | HTR7 (0.38) | HTR7ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL864127 | 0.95 | HTR7 (0.38) | HTR7ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL15184765 | 0.84 | HTR7 (0.43) | HTR7ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL863562 | 0.84 | HTR7 (0.43) | HTR7ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL15184776 | 0.83 | CHRM4 (0.36) | HTR7ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL3714054 | 0.82 | KDM4E (0.37) | KDM4ETLR8TLR7CRHR1PIK3CD | |
| SCHEMBL3714056 | 0.82 | KDM4E (0.37) | KDM4ETLR8TLR7CRHR1PIK3CD | |
| SCHEMBL15184782 | 0.81 | KDM4E (0.35) | HTR7ADRA1DADRA1AADRA1BKDM4E | |
| SCHEMBL15184816 | 0.79 | HTR7 (0.42) | HTR7ADRA1DADRA1AADRA1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396315-B1 | QUINOLINE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB BIOPHARMA SPRL (BE) | 2016-08-31 | — | — | EP | disclosed |
| US-20120077815-A1 | Fused Pyridine And Pyrazine Derivatives As Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077815-A1 | Fused Pyridine And Pyrazine Derivatives As Kinase Inhibitors | PDPK1, PDXK, PIK3CA | HTR7 1818/4885ADRA1D 3469/4885ADRA1A 3834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.