Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645076 | 0.82 | NPC1 (0.68) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL10595285 | 0.77 | NPC1 (0.64) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL11715571 | 0.77 | ALDH1A1 (0.74) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL6361865 | 0.77 | ALDH1A1 (0.74) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL6702998 | 0.77 | ALDH1A1 (0.74) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8641907 | 0.75 | ALDH1A1 (0.62) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL8645072 | 0.75 | NPC1 (0.66) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL16266236 | 0.75 | SMN1; SMN2 (1.00) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL18906003 | 0.75 | ALDH1A1 (0.77) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL27905947 | 0.75 | ALDH1A1 (0.77) | ALDH1A1NPC1RAB9ASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756822-A | ANTIULCER | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |