SCHEMBL8642003

SCHEMBL8642003

CCOC(C)(OC)OC(=O)CCCCC(=O)OC(C)(OC)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
DGKA P23743 1/20 0.34
RECQL P46063 1/20 0.34
CYP1A2 P05177 1/20 0.34
GAA P10253 1/20 0.34
LMNA P02545 4/20 0.33
KMT2A Q03164 1/20 0.33
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PAM P19021 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GLA P06280 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522533 0.90 DGKA (0.38) TSHRDGKARECQLCYP1A2GAA
SCHEMBL522727 0.88 DGKA (0.41) TSHRDGKACYP1A2GAALMNA
SCHEMBL10917111 0.88 DGKA (0.41) TSHRDGKACYP1A2GAALMNA
SCHEMBL10923817 0.86 TSHR (0.41) TSHRDGKACYP1A2GAALMNA
SCHEMBL610468 0.86 TSHR (0.44) TSHRDGKARECQLGAALMNA
SCHEMBL10922395 0.84 TSHR (0.42) TSHRDGKARECQLGAALMNA
SCHEMBL522534 0.83 TSHR (0.44) TSHRLMNAKMT2AALDH1A1MAPT
SCHEMBL10892069 0.83 DGKA (0.50) TSHRDGKALMNAKMT2APAM
SCHEMBL522728 0.81 GPR84 (0.45) TSHRLMNAKMT2APAMALDH1A1
SCHEMBL28854609 0.81 GPR84 (0.45) TSHRLMNAKMT2APAMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11525215-B2 Cellulose and cellulose ester film EASTMAN CHEMICAL COMPANY (US) 2022-12-13 US disclosed
US-11479919-B2 Molded articles from a fiber slurry EASTMAN CHEMICAL COMPANY (US) 2022-10-25 US disclosed
US-11390996-B2 Elongated tubular articles from wet-laid webs EASTMAN CHEMICAL COMPANY (US) 2022-07-19 US disclosed
US-20200063349-A1 ELONGATED TUBULAR ARTICLES FROM WET-LAID WEBS EASTMAN CHEMICAL COMPANY (US) 2020-02-27 US disclosed
US-20200063373-A1 MOLDED ARTICLES FROM A FIBER SLURRY EASTMAN CHEMICAL COMPANY (US) 2020-02-27 US disclosed
US-20200063353-A1 CELLULOSE AND CELLULOSE ESTER FILM EASTMAN CHEMICAL COMPANY (US) 2020-02-27 US disclosed
WO-2020041251-A1 MOLDED ARTICLES FROM A FIBER SLURRY EASTMAN CHEMICAL COMPANY (US) 2020-02-27 WO disclosed
EP-0858530-A1 FILMS MADE FROM PAPER CONTAINING CELLULOSE ESTER FIBER EASTMAN CHEMICAL COMPANY (US) 1998-08-19 EP disclosed
US-5631078-A Films made from paper containing cellulose ester fiber EASTMAN CHEMICAL COMPANY (US) 1997-05-20 US disclosed
WO-1997016599-A1 FILMS MADE FROM PAPER CONTAINING CELLULOSE ESTER FIBER EASTMAN CHEMICAL COMPANY (US) 1997-05-09 WO disclosed