SCHEMBL8642153

SCHEMBL8642153

CNC(=O)NNC(=O)NC

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
RECQL P46063 1/20 0.39
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 1/20 0.35
NOTUM Q6P988 1/20 0.34
POLB P06746 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MCL1 Q07820 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10032154 0.87
SCHEMBL11803871 0.87
SCHEMBL16925899 0.85
SCHEMBL6885012 0.85
SCHEMBL23735554 0.84 CYP1A2 (0.35) ALDH1A1SMN1; SMN2RECQLNOTUMLMNA
SCHEMBL21695702 0.84 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2RECQLNOTUM
SCHEMBL10042 0.82
SCHEMBL8891640 0.80 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2RECQLKDM4EMAPT
SCHEMBL18410285 0.80 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2RECQL
SCHEMBL23676967 0.80 MEN1 (0.36) ALDH1A1SMN1; SMN2NOTUMPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4245751-A1 SEMICARBAZIDE COMPOSITION AND AQUEOUS COATING COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2023-09-20 EP disclosed
US-20150291831-A1 SEMICARBAZIDE COMPOSITION, METHOD FOR PRODUCING SEMICARBAZIDE COMPOSITION, AQUEOUS POLYMER COMPOSITION AND COMPOSITE ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-10-15 US disclosed
US-5731141-A HIGH TEMPERATURE, HIGH SPEED, LOW FOG IMATION CORP. (US) 1998-03-24 US disclosed
EP-0749038-A1 Light-sensitive photographic materials comprising tabular silver halide grains and azodicarbonamide derivatives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291831-A1 SEMICARBAZIDE COMPOSITION, METHOD FOR PRODUCING SEMICARBAZIDE COMPOSITION, AQUEOUS POLYMER COMPOSITION AND COMPOSITE C9, C5, BRD2 ALDH1A1 1195/4885SMN1; SMN2 1642/4885RECQL 1855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.