Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169137 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTKDM4EPKM | |
| SCHEMBL5117928 | 0.80 | CYP2C19 (0.52) | ALDH1A1MAPTKDM4EPKMMEN1 | |
| SCHEMBL8642153 | 0.80 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTKDM4EKMT2A | |
| SCHEMBL15778117 | 0.79 | MCL1 (0.32) | ALDH1A1SMN1; SMN2KDM4ELMNARECQL | |
| SCHEMBL30909396 | 0.77 | MEN1 (0.42) | ALDH1A1SMN1; SMN2MAPTKDM4EPKM | |
| SCHEMBL22074237 | 0.77 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2MAPTKDM4EPKM | |
| SCHEMBL10578591 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4EPKM | |
| SCHEMBL1709868 | 0.76 | — | — | |
| SCHEMBL711913 | 0.75 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTKDM4EPKM | |
| SCHEMBL2242250 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625074-A | Sulphonylaminocarbonyltriazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |
| US-5532378-A | Sulphonylaminocarbonyltriazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0341489-B1 | Sulfonyl amino carbonyl triazolinones | BAYER AG (DE) | 1995-08-23 | — | — | EP | disclosed |
| US-5405970-A | Unique chemical intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-11 | — | — | US | disclosed |
| US-5241074-A | Hherbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| US-5094683-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-5057144-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |
| EP-0341489-A1 | Sulfonyl amino carbonyl triazolinones | BAYER AG (DE) | 1989-11-15 | — | — | EP | disclosed |