Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 16/20 | 0.78 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.65 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.65 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140970 | 0.88 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL101309 | 0.87 | LTA4H (0.65) | LTA4H | |
| SCHEMBL7133844 | 0.86 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7141103 | 0.86 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL8641981 | 0.84 | LTA4H (0.76) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7142372 | 0.84 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7138464 | 0.84 | LTA4H (1.00) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7142393 | 0.82 | LTA4H (0.85) | LTA4H | |
| SCHEMBL7142406 | 0.81 | LTA4H (0.85) | LTA4H | |
| SCHEMBL7142387 | 0.80 | HRH3 (0.97) | LTA4HHRH3PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |