Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LIG1 | P18858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563037 | 0.85 | TSHR (0.56) | TSHRHSD17B10HPGDMAPK1KMT2A | |
| SCHEMBL11828120 | 0.83 | KDM4E (0.56) | HPGDKMT2AMEN1NPC1AKR1C3 | |
| SCHEMBL7957316 | 0.81 | AKR1C3 (0.46) | HPGDKMT2AMEN1AKR1C3ALDH1A1 | |
| SCHEMBL7924940 | 0.80 | KDM4E (0.46) | TSHRHSD17B10HPGDMAPK1KMT2A | |
| SCHEMBL22877265 | 0.78 | HPGD (0.52) | TSHRHSD17B10HPGDMAPK1KMT2A | |
| SCHEMBL2066256 | 0.78 | LMNA (0.62) | MAPK1KMT2AMEN1NPC1AKR1C3 | |
| SCHEMBL3626826 | 0.78 | LMNA (0.62) | MAPK1KMT2AMEN1NPC1AKR1C3 | |
| SCHEMBL6332512 | 0.77 | HPGD (0.62) | TSHRHSD17B10HPGDMAPK1KMT2A | |
| SCHEMBL6332508 | 0.77 | HPGD (0.62) | TSHRHSD17B10HPGDMAPK1KMT2A | |
| SCHEMBL8896498 | 0.76 | AKR1C3 (0.52) | TSHRHSD17B10HPGDMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635536-B1 | Multilayered composite systems | ROEHM GMBH (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0477726-B1 | Ternary mixtures of polymers | ROEHM GMBH (DE) | 1997-03-12 | — | — | EP | disclosed |
| EP-0635536-A1 | Multilayered composite systems | Röhm GmbH (DE) | 1995-01-25 | — | — | EP | disclosed |
| US-5374487-A | Compatible polymeric mixtures | ROHM GMBH (DE) | 1994-12-20 | — | — | US | disclosed |
| US-5250623-A | Compatible polymeric mixtures | ROHM GMBH (DE) | 1993-10-05 | — | — | US | disclosed |
| EP-0477726-A1 | Ternary mixtures of polymers | RÖHM GMBH (DE) | 1992-04-01 | — | — | EP | disclosed |
| WO-1991011490-A1 | COMPATIBLE POLYARYLACRYLATE AND POLYESTER MIXTURES | RÖHM GMBH (DE) | 1991-08-08 | — | — | WO | disclosed |
| EP-0440034-A1 | Compatible polymer blends | RÖHM GMBH (DE) | 1991-08-07 | — | — | EP | disclosed |