Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.52 |
| ▸ | CDK2 | P24941 | 3/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.41 |
| ▸ | PDE8A | O60658 | 3/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22304003 | 0.73 | PIK3CD (0.42) | PIK3CDPDE10A | |
| SCHEMBL864009 | 0.72 | PIK3CD (0.41) | PIK3CDPDE10A | |
| Hydrochloric Acid SCHEMBL863977 | 0.71 | LMNA (0.49) | PIK3CDPDE10A | |
| Hydrochloric Acid SCHEMBL863976 | 0.71 | LMNA (0.49) | PIK3CDPDE10A | |
| SCHEMBL29611365 | 0.70 | CDK1 (1.00) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL756644 | 0.70 | CDK1 (1.00) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL864264 | 0.70 | PIK3CD (0.40) | PIK3CD | |
| SCHEMBL24239234 | 0.69 | CDK1 (0.78) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL29248683 | 0.68 | PIK3CD (0.58) | CDK1CCNB1CCNE1CDK2PIK3CD | |
| SCHEMBL28083712 | 0.68 | CDK1 (0.76) | CDK1CCNB1CCNE1CDK2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077815-A1 | Fused Pyridine And Pyrazine Derivatives As Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077815-A1 | Fused Pyridine And Pyrazine Derivatives As Kinase Inhibitors | PDPK1, PDXK, PIK3CA | CDK1 120/4885CCNB1 2015/4885CCNE1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.