Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.59 |
| ▸ | ITGAV | P06756 | 18/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7403601 | 0.84 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL5027067 | 0.84 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL6111422 | 0.84 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL8547845 | 0.82 | ITGB3 (0.52) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL13059980 | 0.82 | ITGB3 (0.54) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL8682272 | 0.82 | ITGB3 (0.65) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL8682237 | 0.82 | ITGB3 (0.61) | ITGB3ITGAVITGA2BMALT1 | |
| SCHEMBL7401332 | 0.81 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL7401335 | 0.81 | ITGB3 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL8682694 | 0.81 | ITGB3 (0.64) | ITGB3ITGAVITGA2BMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | claimed |
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | disclosed |
| US-5710159-A | IMIDAZOLIN-2-YLAMINOPROPOXY)ISOXAZOL-5-CARBONYLAMINO-2 -BENZYLOXYCARBONYLAMINOPROPIONIC ACID AS ANTIINFLAMMATORY AGENTS, BONE DEGRADATION, TUMORS, METASTASES AND THROMBOSIS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-20 | — | — | US | disclosed |