Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643261 | 1.00 | HDAC4 (0.40) | HDAC4OPRL1OPRM1OPRK1HSD11B1 | |
| SCHEMBL731291 | 0.81 | HDAC4 (0.40) | HDAC4OPRL1OPRM1OPRK1HSD11B1 | |
| SCHEMBL8636073 | 0.76 | SLC6A3 (0.38) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8636069 | 0.76 | SLC6A3 (0.38) | OPRL1OPRM1OPRK1 | |
| SCHEMBL9849441 | 0.74 | OPRL1 (0.35) | HDAC4OPRL1OPRM1OPRK1LMNA | |
| SCHEMBL9344143 | 0.73 | HDAC4 (0.33) | HDAC4OPRL1OPRM1OPRK1HSD11B1 | |
| SCHEMBL19171686 | 0.73 | HDAC4 (0.39) | HDAC4OPRL1OPRM1OPRK1HSD11B1 | |
| SCHEMBL731689 | 0.72 | HDAC4 (0.35) | HDAC4OPRL1OPRM1OPRK1CYP2C9 | |
| SCHEMBL8638484 | 0.72 | MEN1 (0.33) | OPRL1OPRM1OPRK1ALDH1A1MAPT | |
| SCHEMBL8638481 | 0.72 | MEN1 (0.33) | OPRL1OPRM1OPRK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |