Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636069 | 1.00 | SLC6A3 (0.38) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL8640296 | 0.83 | CYP3A4 (0.33) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL8640293 | 0.83 | CYP3A4 (0.33) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL10015002 | 0.81 | SLC6A3 (0.45) | SLC6A3SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL8638484 | 0.77 | MEN1 (0.33) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8638481 | 0.77 | MEN1 (0.33) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8643261 | 0.76 | HDAC4 (0.40) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8643255 | 0.76 | HDAC4 (0.40) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8638506 | 0.75 | MEN1 (0.33) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8638501 | 0.75 | MEN1 (0.33) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571652-B1 | Liquid crystalline substituted dihydrobenzene derivatives | CITIZEN WATCH CO LTD (JP) | 1998-08-05 | — | — | EP | disclosed |
| US-5342546-A | Liquid crystal compositions | L.C.C. CONSULTANTS CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0571652-A1 | Liquid crystalline substituted dihydrobenzene derivatives | L.C.C. CONSULTANTS CO., LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |