Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8648370 | 0.92 | MEN1 (0.33) | MAPTMEN1KMT2ASMN1; SMN2GCGR | |
| Trifluoroacetic Acid SCHEMBL8643486 | 0.90 | CTDSP1 (0.35) | MAPTMEN1KMT2ASMN1; SMN2GCGR | |
| SCHEMBL8646473 | 0.90 | MEN1 (0.34) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| Trifluoroacetic Acid SCHEMBL8642849 | 0.89 | CTDSP1 (0.33) | MAPTMEN1KMT2ASMN1; SMN2GCGR | |
| SCHEMBL8643880 | 0.89 | MEN1 (0.34) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL8643119 | 0.88 | ALDH1A1 (0.35) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL8644211 | 0.87 | MAPT (0.36) | MAPTMEN1KMT2ASMN1; SMN2GCGR | |
| SCHEMBL8645977 | 0.86 | POLB (0.37) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL8646015 | 0.85 | MEN1 (0.39) | MAPTMEN1KMT2ASMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL8644811 | 0.85 | POLB (0.36) | MAPTMEN1KMT2ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |