Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8644811 | 0.99 | POLB (0.36) | POLBCTDSP1TDP1ESRRGRAB9A | |
| Trifluoroacetic Acid SCHEMBL8643486 | 0.96 | CTDSP1 (0.35) | POLBCTDSP1TDP1ESRRGRAB9A | |
| SCHEMBL8644211 | 0.88 | MAPT (0.36) | POLBCTDSP1TDP1ESRRGRAB9A | |
| SCHEMBL8648975 | 0.88 | MAPT (0.35) | POLBCTDSP1TDP1ESRRGRAB9A | |
| Hydrochloric Acid SCHEMBL8643305 | 0.88 | MAPT (0.35) | POLBCTDSP1TDP1ESRRGRAB9A | |
| SCHEMBL8646015 | 0.86 | MEN1 (0.39) | POLBCTDSP1TDP1RAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL8644126 | 0.86 | MAPT (0.35) | POLBCTDSP1TDP1ESRRGRAB9A | |
| SCHEMBL8643880 | 0.86 | MEN1 (0.34) | POLBCTDSP1TDP1ESRRGRAB9A | |
| Hydrochloric Acid SCHEMBL8647775 | 0.85 | MEN1 (0.38) | POLBCTDSP1TDP1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8643119 | 0.85 | ALDH1A1 (0.35) | POLBCTDSP1TDP1ESRRGRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |