Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8648666 | 0.95 | ALDH1A1 (0.38) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8648196 | 0.88 | HDAC1 (0.46) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8649037 | 0.86 | ATM (0.42) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8643120 | 0.86 | MAPT (0.51) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8649382 | 0.83 | F7 (0.39) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8644572 | 0.83 | CYP1A1 (0.54) | ALDH1A1POLBNPC1RAB9AMAPT | |
| SCHEMBL8645267 | 0.83 | CYP1A1 (0.47) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8648668 | 0.82 | ALDH1A1 (0.35) | ALDH1A1TDP1HDAC1HDAC3HDAC2 | |
| SCHEMBL8644380 | 0.82 | MAPT (0.45) | F7F3SARM1SIRT2SIRT6 | |
| SCHEMBL8647081 | 0.82 | MAPT (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861831-A1 | HETEROARYL-SUBSTITUTED ACRYLOYLGUANIDINE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |