Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 3/20 | 0.83 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.83 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.83 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.83 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.83 |
| ▸ | FGR | P09769 | 1/20 | 0.83 |
| ▸ | PIM1 | P11309 | 1/20 | 0.83 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.83 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 8/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.71 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | PLEC | Q15149 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29361319 | 0.91 | ADORA2A (1.00) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL525762 | 0.91 | ADORA2A (1.00) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL10904540 | 0.89 | ADORA2A (0.95) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| Ammonia Solution, Strong SCHEMBL28091930 | 0.89 | ADORA2A (0.95) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| Hydrochloric Acid SCHEMBL8643536 | 0.89 | ADORA2A (0.95) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL28600074 | 0.88 | ADORA2A (0.70) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL14988943 | 0.87 | ADORA2A (0.68) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| Sulfuric Acid SCHEMBL28138466 | 0.86 | ADORA2A (0.85) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL29529563 | 0.84 | ADORA2A (0.86) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL29548552 | 0.84 | ADORA2A (0.86) | ADORA2AMAOACSNK1A1CSNK1DCSNK1G1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56090053-A | — | — | None | — | — | JP | disclosed |
| US-5821320-A | MIXING AROMATIC DIAMINE DIHYDROCHLORIDE OR SULFATE WITH AROMATIC ACID DIANHYDRIDE, HEATING TO DEHYDRATE AND CONDENSE | PETROLEUM ENERGY CENTER (JP) | 1998-10-13 | — | — | US | disclosed |
| JP-S5690053-A | PREPARATION OF 1,4-DIAMINOANTHRAQUINONE-2-SULFONIC ACID | SUMITOMO CHEM CO LTD | 1981-07-21 | — | — | JP | disclosed |