SCHEMBL14988943

SCHEMBL14988943

Nc1ccc(S(=O)(=O)O)c2c1C(=O)c1ccccc1C2=O.[NaH]

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 4/20 0.68
MAOA P21397 3/20 0.68
CSNK1A1 P48729 2/20 0.68
CSNK1D P48730 2/20 0.68
CSNK1G1 Q9HCP0 2/20 0.68
FGR P09769 1/20 0.68
PIM1 P11309 1/20 0.68
DYRK1A Q13627 1/20 0.68
HIPK2 Q9H2X6 1/20 0.68
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
POLB P06746 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
MCL1 Q07820 2/20 0.61
PABPC1 P11940 1/20 0.61
HPGD P15428 1/20 0.61
BLM P54132 1/20 0.61
PLEC Q15149 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
MAPT P10636 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28600074 0.98 ADORA2A (0.70) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL2854714 0.89 PGAM1 (0.59) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
Sulfuric Acid SCHEMBL8644268 0.87 ADORA2A (0.83) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL525762 0.82 ADORA2A (1.00) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL29361319 0.82 ADORA2A (1.00) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL27791137 0.82 MEN1 (0.68) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL11062566 0.82 ADORA2A (0.57) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL28420647 0.81 GNG2 (0.59) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL9558889 0.81 MAOA (0.51) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1
SCHEMBL12477906 0.81 ADORA2A (0.59) ADORA2AMAOACSNK1A1CSNK1DCSNK1G1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180036995-A1 HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME MITSUI CHEMICALS, INC. (JP) 2018-02-08 US disclosed
EP-3270192-A1 HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF Mitsui Chemicals, Inc. (JP) 2018-01-17 EP disclosed
EP-2599799-B1 SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING SAME MITSUI CHEMICALS INC (JP) 2016-05-25 EP disclosed
US-9034464-B2 Single layer film and hydrophilic material comprising the same MITSUI CHEMICALS, INC. (JP) 2015-05-19 US disclosed
US-20150126682-A1 HYDROPHILIC MODIFIED ACRYLIC RESIN FILM MITSUI CHEMICALS, INC. (JP) 2015-05-07 US disclosed
EP-2860215-A1 MODIFIED HYDROPHILIC ACRYLIC RESIN FILM Mitsui Chemicals, Inc. (JP) 2015-04-15 EP disclosed
US-20130156959-A1 SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING THE SAME MITSUI CHEMICALS, INC. (JP) 2013-06-20 US disclosed
EP-2599799-A1 SINGLE-LAYER FILM AND HYDROPHILIC MATERIAL COMPRISING SAME Mitsui Chemicals, Inc. (JP) 2013-06-05 EP disclosed