Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8646799 | 0.99 | ITGB3 (0.46) | ITGB3ITGA2BNPC1RAB9ASCN5A | |
| SCHEMBL8646001 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BALDH1A1KDM4EF2 | |
| Hydrochloric Acid SCHEMBL8647767 | 0.91 | ITGB3 (0.44) | ITGB3ITGA2BALDH1A1KDM4EF2 | |
| SCHEMBL8644198 | 0.85 | F10 (0.40) | ITGB3ITGA2BPRSS1F2F10 | |
| SCHEMBL8644302 | 0.85 | NPC1 (0.42) | NPC1RAB9ASCN5ASCN2AGAA | |
| Hydrochloric Acid SCHEMBL8646804 | 0.84 | NPC1 (0.42) | NPC1RAB9ASCN5ASCN2AGAA | |
| Trifluoroacetic Acid SCHEMBL8644121 | 0.83 | KLK1 (0.41) | ITGB3ITGA2BF2F10 | |
| Trifluoroacetic Acid SCHEMBL8646468 | 0.83 | KLK1 (0.43) | ITGB3ITGA2BF2F10 | |
| SCHEMBL8645969 | 0.82 | F10 (0.40) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8644799 | 0.81 | F10 (0.40) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726185-A | BINDING OF ADHESIVE PROTEINS TO BLOOD PLATELET AGGREGATION AND CELL TO CELL ADHESION | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |