Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138165 | 0.89 | TSHR (0.44) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL27552377 | 0.88 | KDM4E (0.50) | ALDH1A1KMT2ASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL26566774 | 0.84 | LMNA (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1KDM4E | |
| SCHEMBL17055505 | 0.81 | KDM4E (0.48) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL9304892 | 0.81 | CYP1A2 (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL1794534 | 0.81 | KDM4E (0.48) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL17138134 | 0.80 | L3MBTL1 (0.46) | ALDH1A1KMT2AMEN1GAATSHR | |
| SCHEMBL17138201 | 0.79 | PRSS1 (0.43) | ALDH1A1GAATSHRL3MBTL1 | |
| SCHEMBL19748762 | 0.78 | CYP1A2 (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL17138193 | 0.76 | KMT2A (0.47) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723666-A | USEFUL AS REGULATORS OF CELL PROLIFERATION AND DIFFERENTIATION | ALLERGAN (US) | 1998-03-03 | — | — | US | disclosed |