Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312252 | 0.87 | PAM (0.52) | HDAC1PAMTRPA1ALDH1A1LMNA | |
| SCHEMBL14312251 | 0.87 | PAM (0.52) | HDAC1PAMTRPA1ALDH1A1LMNA | |
| SCHEMBL14312254 | 0.87 | PAM (0.52) | HDAC1PAMTRPA1ALDH1A1LMNA | |
| SCHEMBL95863 | 0.87 | PAM (0.56) | HDAC2HDAC1HDAC6PAMTRPA1 | |
| SCHEMBL1817496 | 0.87 | PAM (0.56) | HDAC2HDAC1HDAC6PAMTRPA1 | |
| SCHEMBL31634334 | 0.84 | HDAC2 (0.44) | HDAC2MGLLCA1GRIK1GRIK2 | |
| SCHEMBL17291648 | 0.82 | TRIM24 (0.45) | HDAC2CA1HDAC1PAMALDH1A1 | |
| SCHEMBL31634319 | 0.80 | GRIK1 (0.41) | HDAC2MGLLCA1GRIK1GRIK2 | |
| SCHEMBL17181677 | 0.77 | CA1 (0.48) | HDAC2MGLLCA1GRIK1GRIK2 | |
| SCHEMBL11252486 | 0.77 | CA1 (0.48) | HDAC2MGLLCA1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830441-A | SUNSCREEN AGENTS | ISP INVESTMENTS INC. (US) | 1998-11-03 | — | — | US | disclosed |