SCHEMBL1817496

SCHEMBL1817496

O=CC/C=C/c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.56
ALDH1A1 P00352 5/20 0.52
LMNA P02545 2/20 0.52
TRPA1 O75762 1/20 0.52
ALOX5 P09917 1/20 0.52
MAPK1 P28482 1/20 0.52
IDO1 P14902 2/20 0.50
MAOB P27338 2/20 0.48
CYP2A6 P11509 1/20 0.48
HTR2A P28223 3/20 0.47
MAPT P10636 2/20 0.44
HDAC3 O15379 1/20 0.44
TNKS O95271 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95863 1.00 PAM (0.56) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL14312252 0.95 PAM (0.52) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL14312254 0.95 PAM (0.52) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL14312251 0.95 PAM (0.52) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL8644372 0.87 HDAC2 (0.47) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL9777486 0.84 IDO1 (0.58) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL4863423 0.84 IDO1 (0.58) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL17291648 0.82 TRIM24 (0.45) PAMALDH1A1MAOBCYP2A6HDAC1
SCHEMBL2399949 0.81 PAM (0.52) PAMALDH1A1LMNATRPA1ALOX5
SCHEMBL97315 0.81 PAM (0.52) PAMALDH1A1LMNATRPA1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3455184-B1 MINERAL WOOL PRODUCT ROCKWOOL INT (DK) 2021-12-08 EP claimed
CN-113429307-A Preparation method and application of stable isotope labeled glutamic acid and glutamic acid derivative 深圳鼎邦生物科技有限公司 2021-09-24 CN claimed
US-20210235723-A1 APPLICATION OF CINNAMALDEHYDE AND/OR ALLANTOIN TO REPLACE HIGH ZINC AMOUNTS IN SUCKLING PIGLET FEED, FEED ADDITIVE OR ADDITIVE PREMIX, AND FEED HUNAN JINGTIAN TECHNOLOGY INDUSTRY CO., LTD. (CN) 2021-08-05 US claimed
EP-3804529-A1 APPLICATION OF CINNAMALDEHYDE AND/OR ALLANTOIN TO REPLACE HIGH ZINC AMOUNTS IN SUCKLING PIGLET FEED, FEED ADDITIVE OR ADDITIVE PREMIX, AND FEED Hunan Jingtian Technology Industry Co., Ltd. (CN) 2021-04-14 EP claimed
CN-107498667-B A kind for the treatment of process improving wood preservation performance using cinnamylaldehyde derivatives 阜南县中泰工艺品有限公司 2019-10-18 CN claimed
CN-106831641-B Benzothiazole derivatives and preparation method thereof 浙江工业大学 2019-03-19 CN claimed
CN-109021717-A One kind being suitable for wicker products dyestuff 阜南县猛发工艺品有限公司 2018-12-18 CN claimed
CN-108623807-A A kind of response type polymer nano-particle and preparation method thereof based on cinnamic acid 温州大学 2018-10-09 CN claimed
CN-106518715-B A kind of preparation method and purposes of chemiluminescence sensing material 江苏大学 2018-06-01 CN claimed
CN-107873419-A A kind of tomato planting method 蚌埠市徽吉星农业科技农民专业合作社 2018-04-06 CN claimed
US-20100048699-A1 CHEMICAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-02-25 US claimed
CN-101291902-A Method for continuous hydrogenation or hydrogenation amination BASF SE (DE) 2008-10-22 CN claimed
CN-1252020-C Process for producing cinnamaldehyde derivative, use thereof, and the like AJINOMOTO KK (JP) 2006-04-19 CN claimed
CN-1193972-C Continuous method for production of cinnamaldehyde and dihydrocinnamaldehyde derivatives BASF AG (DE) 2005-03-23 CN claimed
CN-1429193-A Process for producing cinnamylaldehyde derivatives, use thereof and the like AJINOMOTO KK (JP) 2003-07-09 CN claimed
CN-1379750-A Continuous method for production of cinnamaldehyde and dihydrocinnamaldehyde derivatives BASF AG (DE) 2002-11-13 CN claimed
CN-1378559-A Process for producing aspartyl dipeptide ester derivative, novel production intermediate therefor, and process for producing the intermediate AJINOMOTO KK (JP) 2002-11-06 CN claimed
CN-1376660-A Synthesis of substituted trans-cinnamic aldehyde-natural yellow dyestuff from phenylpropyl alkyl derivatives COUNCIL SCIENT IND RES (IN) 2002-10-30 CN claimed
CN-1213364-A Cinnamylidene camphor derivatives and their use as UV-A protecting agents BASF AG (DE) 1999-04-07 CN claimed
US-4006163-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1977-02-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048699-A1 CHEMICAL COMPOUNDS ACHE, TYR, SGMS1 PAM 1483/4885ALDH1A1 128/4885LMNA 1673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.