Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8644275 | 0.92 | UTS2R (0.46) | DRD2DRD3DRD4DRD5HTR1A | |
| SCHEMBL8648283 | 0.91 | DRD2 (0.44) | DRD2DRD3DRD4DRD5HTR1A | |
| SCHEMBL8644510 | 0.90 | DRD2 (0.45) | DRD2DRD3DRD4DRD5HTR1A | |
| SCHEMBL8644873 | 0.89 | DRD2 (0.48) | DRD2DRD3DRD4DRD5HTR1A | |
| SCHEMBL8643939 | 0.86 | DRD2 (0.49) | DRD2DRD3DRD4DRD5HTR1A | |
| Fumaric Acid SCHEMBL8647009 | 0.84 | NPC1 (0.43) | DRD2DRD3DRD4DRD5HTR1A | |
| Fumaric Acid SCHEMBL8650993 | 0.83 | NPC1 (0.42) | DRD2DRD3DRD4DRD5HTR1A | |
| Fumaric Acid SCHEMBL8646610 | 0.83 | DRD2 (0.43) | DRD2DRD3DRD4DRD5HTR1A | |
| SCHEMBL8649737 | 0.81 | NPC1 (0.49) | DRD2DRD3DRD4DRD5HTR1A | |
| Fumaric Acid SCHEMBL8649719 | 0.80 | HTR1A (0.44) | DRD2HTR1AHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |