Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963900 | 0.87 | LDHA (0.66) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| SCHEMBL4998033 | 0.86 | LDHA (0.64) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| SCHEMBL25321413 | 0.83 | LDHA (0.64) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| SCHEMBL30474585 | 0.83 | LDHA (0.64) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| SCHEMBL6441639 | 0.81 | ALDH1A1 (0.67) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| SCHEMBL9244545 | 0.81 | LDHA (0.82) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| SCHEMBL3291118 | 0.81 | ALDH1A1 (0.67) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| Hydrochloric Acid SCHEMBL3268062 | 0.80 | ALDH1A1 (0.70) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| SCHEMBL9438086 | 0.80 | LDHA (0.69) | LDHAALDH1A1ALOX15ALOX12NPC1 | |
| Hydrochloric Acid SCHEMBL3291115 | 0.80 | ALDH1A1 (0.70) | LDHAALDH1A1ALOX15ALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703919-B1 | PHOSPHOSUCCINIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1998-09-02 | — | — | EP | disclosed |
| US-5683994-A | BONE DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-11-04 | — | — | US | disclosed |
| EP-0703919-A1 | PHOSPHOSUCCINIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995000522-A1 | PHOSPHOSUCCINIC ACID DERIVATIVES AND THEIR USE AS MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1995-01-05 | — | — | WO | disclosed |